ea0029p1163 | Nuclear receptors and Signal transduction | ICEECE2012
Vendelbo M.
, Jorgensen J.
, Jessen N.
, Moller N.
Background: Intermittent fasting increase maximum lifespan in several species and this effect is associated with reduced protein synthesis signaling. During fasting, a progressive loss of protein in human skeletal muscle is evident. Furthermore, fasting is associated with increased lipid oxidation and insulin resistance.Aim: To define which protein metabolic mechanisms are activated in skeletal muscle during fasting.Methods: We inv...